Cationic liposome–nucleic acid nanoparticle assemblies with applications in gene delivery and gene silencing
نویسندگان
چکیده
منابع مشابه
Cationic liposome-nucleic acid complexes for gene delivery and gene silencing.
Cationic liposomes (CLs) are studied worldwide as carriers of DNA and short interfering RNA (siRNA) for gene delivery and gene silencing, and related clinical trials are ongoing. Optimization of transfection efficiency and silencing efficiency by cationic liposome carriers requires a comprehensive understanding of the structures of CL-nucleic acid complexes and the nature of their interactions ...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
سال: 2016
ISSN: 1364-503X,1471-2962
DOI: 10.1098/rsta.2015.0129